Immunofluorescent detection of herpesvirus antigens in exfoliated cells from human cervical carcinoma.
نویسندگان
چکیده
Exfoliated cells from patients with squamous carcinoma of the cervix contain antigens related to herpesvirus subtype 2, as revealed by direct or indirect immunofluorescent techniques. Normal squamous cells from the same subjects and from controls without the disease, and cells from a small number of tumors at sites other than the cervix, did not react with anti-herpesvirus subtype 2 serum. Antisera to adenovirus 18 or mycoplasma orale did not react with the exfoliated cells.
منابع مشابه
Virions and antigens of herpes virus type 2 in cervical carcinoma.
Herpesvirus type 2 (HSV-2) has been associated with squamous cancer of the human cervix on the basis of seroepidemiological data. Findings providing information on the basis of the association of the HSV-2 genome with cervical cancer cells are presented. A herpesvirus isolated from de generated cervical tumor cells grown in vitro is identified as a type 2 on the basis of biological and immunolo...
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 67 1 شماره
صفحات -
تاریخ انتشار 1970